Research / Chemistry across worlds

How does life become possible?

Earth gives us the only known example of life taking hold on a planet. I study how its chemistry may have begun and what those origins can teach us about life’s possibilities elsewhere. My first few projects explore Venus’s sulfuric-acid clouds and Titan’s temporary melt pools.

Research projects

False-color composite of Titan with Selk crater marked by a yellow box.Titan

Saturn’s largest moon

Could a temporary melt pool help assemble life’s ingredients?

An impact can briefly turn Titan’s icy surface into liquid water. I study what chemistry might become possible in that temporary window.

NASA / JPL / University of Arizona / CNRS / LPG. False-color composite; Selk crater is highlighted.

Published molecular models of a phosphorus-sulfur ring and its precursor.Venus

The clouds of our planetary neighbor

Could unfamiliar chemistry emerge in sulfuric-acid clouds?

Life on Earth gives us one chemical example. This study asks whether carbon-free polymer structures could be plausible in a very different planetary setting.

Madan et al. (2025), Figure 3, cropped. QRB Discovery. CC BY 4.0.

From possibility to a testable question

How I work

Model the chemistry

Use computational chemistry to test how life’s ingredients could form on Earth and other worlds.

Build useful workflows

Build tools that make chemical calculations easier to run, connect, and compare.

Make the work approachable

Turn papers into visual explanations, interactive experiences, and talks that invite people into the questions.

The published work

Selected publications

My ORCID record (opens in a new tab)
  1. 2026

    Prebiotic Chemistry Insights for Dragonfly. II. Thermodynamic Favorability of Nucleobases, Ribose, and Fatty Acids in Selk Crater on Titan (opens in a new tab)

    Ishaan Madan & Ben K. D. Pearce · The Planetary Science Journal 7, 107

  2. 2025

    Prebiotic Chemistry Insights for Dragonfly: Thermodynamics of Amino Acid Synthesis in Selk Crater on Titan (opens in a new tab)

    Ishaan Madan & Ben K. D. Pearce · The Planetary Science Journal 6, 284

  3. 2025

    On the possibility of carbon-free heteropolymers on Venus: a computational astrobiology study (opens in a new tab)

    Ishaan Madan, Shekoufeh Arabi Aliabadi, et al. · QRB Discovery 6, e23

    All authors

    Ishaan Madan, Shekoufeh Arabi Aliabadi, Johanna Huhtasaari, Ebba Matic, Emil Hogedal, Kinga Kamińska, Filip Nilsson, Axel Stark, Fernando Izquierdo-Ruiz, Hilda Sandström, Martin Rahm